Date published: 2007/05/01
The BBC says:
Healthy older people who take regular aspirin to prevent stroke may actually be increasing their risk.
In the past 25 years the number of strokes associated with blood-thinning drugs such as aspirin or warfarin has risen seven-fold, a UK study found.
The risk is particularly high in the over 75s and aspirin may do more harm than good in healthy older people, The Lancet Neurology paper reported.
However, people advised to take daily aspirin by their GP should not stop. v Researchers at the University of Oxford compared figures on intracerebral haemorrhagic stroke - a type of stroke caused by bleeding in the brain - from 1981-85 and 2002-06.
They found that the number of strokes caused by high blood pressure had fallen by 65%, which in the under 75s meant the overall rate of strokes had halved.
But in the over 75s the stroke rate remained the same over the 25-year period.
A closer look at the data showed there had been an increase in the number of strokes in patients taking blood thinning drugs, known as antithrombotics.
In the first study the proportion of stroke patients on antithrombotic drugs was 4% but two decades later this had risen to 40%.
People with cardiovascular disease, who have a high risk of blood clot, are prescribed drugs like aspirin to thin the blood and reduce the risk of a heart attack or stroke.
But many healthy older people also take a regular aspirin in an attempt to ward off a stroke.
Study leader, Professor Peter Rothwell, said the increasing use of drugs such as aspirin may soon take over high blood pressure as the leading cause of intracerebral haemorrhagic stroke in the over 75s.
He warned than in healthy older adults the risks of taking aspirin may outweigh any benefits.
"GPs have been treating high blood pressure very aggressively and that is bringing dividends but there are other causes of stroke in the elderly which have become important.
"There are good reasons for taking aspirin or warfarin but there are elderly who take aspirin as a lifestyle choice and in that situation the trials have shown there's no benefit.
"And what our study suggests is that, particularly in the very elderly, the risks of aspirin outweigh the benefits," he said.
Nobody should be taking drugs unless there is a good reason. Unfortunately the BBC has so garbled this story that it's hard to know if there really is as bad a problem here as they suggest. For one thing, they talk about both the "number of strokes" and the "rate of strokes". The number of strokes is a fairly meaningless statistic because the number of people over 75 must have been higher in 2002-6 than in 1981-5, so you would expect more strokes. It is the rate of strokes (i.e. the number of strokes per capita) that really counts. The article then claims the stroke rate for the over 75s "remained the same over the 25-year period". If the stroke rate is the same then a natural conclusion is that some things might have made it better and some worse, but on average nothing has changed. So why pick on one factor as allegedly a problem? And it's also possible that the people who survived past 75 in 2002-6 whose peers would have died in 1981-5 are more susceptible to strokes. All in all, it's best to take most health stories on the BBC website with a pinch of salt.
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